She entered Hindi film industry in 2005 with Garam Masala in which she portrayed Sweety, an airhostess. She also acted in Telugu film Godavari in 2006.
In 2007 she appeared in Madhur Bhandarkar's film, Traffic Signal. She spent a whole week living on the streets of Mumbai and living by a traffic light, to study the character.
In the year 2008, she had four releases by Directors, Dibakar Banerjee, Rahul Dholakia, Ashwini Dheer and Vikram. Her Tamil film, Yavarum Nalam with Madhavan released in the year 2009 was declared a major hit. Currently, Neetu is working on a major project, Jag Mundhra's Apartment.
In 2013 she acted in a gangster movie Ameerin Aadhi Baghavan with Jayam Ravi.
